Typical Kawasaki disease

Kawasaki disease (KD) was first described in Japan in 1967 by Tomisaku Kawasaki [1]. It is an acute, systemic, self-limited vasculitis, whose targets are medium diameter vessels in each organ and apparatus. It is a vasculitis of unknown aetiology, probably multifactorial, that occurs predominantly in infants and young children. The most important complications are coronary arteries aneurysms or ectasia, that develop in 15% to 25% of untreated patients, but only in 5% of patients treated with immunoglobulins within ten days following onset of fever [2,3]. Typical Kawasaki disease is characterized by signs and symptoms which are defined as “diagnostic clinical criteria”, and are: